Genetic examinations list

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Predictive testing – a partner carries the gene mutation from CarrierTest (including compatibility of the couple)

CarrierTest is a panel NGS test of selected regions using data from exome libraries.

When to use this test: The partner is already a known carrier of the gene mutation detected in our laboratory by CarrierTest. Therefore, the patient is indicated to be tested for all mutations of the gene, which will also be performed by CarrierTest and the compatibility of both partners determined.

Material:

Peripheral blood, Isolated DNA from blood

Turnover Time:

6 weeks

STATIM

3 weeks

Predictive testing of known familial gene mutation from CarrierTest

Testing for carriage of familial pathogenic mutations detected during testing in the CarrierTest panel NGS test.

Material:

Peripheral blood, Buccal swab …
Peripheral blood, Buccal swab, Isolated DNA from blood, Isolated DNA from chorionic villi, Isolated DNA from amniotic fluid, Isolated DNA from cordocentesis, DNA isolated from the product of conception, Cultured cells

Turnover Time:

3 weeks

STATIM

1 week

Predictive testing – a partner carries the gene mutation from CarrierTest but not tested in GNTlabs

CarrierTest is a panel NGS test of selected regions using data from exome libraries.

When to use this test: The partner is already a known carrier of a mutation in the gene that is included in the CarrierTest, so the patient is indicated to be tested for all mutations in the gene, which will also be performed by CarrierTest, but the partner has not been tested in our laboratory and compatibility will not be tested.

Material:

Peripheral blood, Isolated DNA from blood

Turnover Time:

6 weeks

STATIM

3 weeks

PGT-M direct embryo sequencing

Testing for the presence of a known mutation in an embryo originating from one parent using (Sanger) sequencing of a specific region. Can only be done in conjunction with the PGT-M karyomapping method.

Material:

Trophectoderm, Amplified DNA from the trophectoderm

Turnover Time:

4 weeks

STATIM

2 weeks

PRENASCAN

Screening of cell-free foetal DNA (cfDNA) from the blood of a pregnant woman to detect aneuploidy of sex and non-sex chromosomes of the aborted foetus and its gender. From week 10 of the pregnancy.

Material:

Peripheral blood

Turnover Time:

2 weeks

STATIM

1 week

Testing for maternal contamination

Testing of maternal contamination of material after collection by invasive techniques, using QF-PCR.

Material:

Peripheral blood, Isolated DNA from blood

STATIM

2 days